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PubMed · 2072877

Uterine collagen during involution in cattle.

R Kaidi·P J Brown·J S David·D J Etherington·S P Robins
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Abstract

Post-partum involution of the bovine uterus was assessed by clinical examination and monitored biochemically by measuring the total urinary excretion of hydroxyproline and the collagen cross-link, pyridinoline. Uterine tissue contained 0.13 +/- 0.04 residues of pyridinoline per mole of collagen and negligible (less than 0.005 residues/mole) deoxypyridinoline. The pyridinoline/creatinine ratio was found to be a clearer and more reliable indicator of uterine resorption than the hydroxyproline/creatinine ratio. The amount of collagen cross-link excreted above baseline was equivalent to the amount of cross-link estimated to have been accumulated during pregnancy. Maximal excretion of pyridinoline occurred at day 6 and returned to baseline values in 2-3 weeks after parturition. An electron microscope study during the period of peak resorption revealed macrophage-like cells apparently engulfing or containing collagenous material, indicating phagocytic removal of the connective tissue.

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Amino AcidsAnimalsCattleCollagenFemaleHydroxyprolineMicroscopy, ElectronPostpartum PeriodPregnancyUterusJournal ArticleResearch Support, Non-U.S. Gov't

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R Kaidi, P J Brown, J S David, D J Etherington, S P Robins. 1991. Uterine collagen during involution in cattle.. https://doi.org/10.1016/s0934-8832(11)80213-1

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