[Endothelial reparative regeneration--a self-regulating process?].

M D Rekhter; A A Mironov

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PubMed · 2073151

[Endothelial reparative regeneration--a self-regulating process?].

M D Rekhter·A A Mironov

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Abstract

When investigating dynamics of reparative regeneration of the rat aorta endothelium after injuring a considerable area by means of cryogenic lesion, a certain tendency to cluster arrangement of proliferating endothelial cells (EC) has been revealed at the edge of the defect both at the beginning and at the end of the reparative process. This fact together with the data on mechanisms of migration and proliferation of EC makes it possible to suppose certain scheme of the mitotic reaction development in endothelium. It consists of centropetal movement of waves of interdependent acts of contraction and flattening of endotheliocytes. Some characteristics of the regenerative proliferation of endothelium make it possible to formulate a hypothesis on autowave character of its regulation.

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Animals Aorta, Abdominal Cell Division Endothelium, Vascular In Vitro Techniques Microscopy, Electron Models, Cardiovascular Rats Wound Healing English Abstract Journal Article

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M D Rekhter, A A Mironov. 1990. [Endothelial reparative regeneration--a self-regulating process?].. https://pubmed.ncbi.nlm.nih.gov/2073151/

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