PubMed · 2081661
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
P C Briggs. 1990. Burns--a continuing tragedy.. https://pubmed.ncbi.nlm.nih.gov/2081661/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
Reports that examined the issue of whether transplantation of inadequate nephron mass may be a risk factor for long-term allograft failure yielded conflicting results. One of the more accurate methods of estimating glomerular mass is kidney weight. Most of the clinical studies used body surface area (BSA) or kidney length as estimates of kidney weight. To test the hypothesis that indirect measures of kidney weight are accurate estimates of kidney weight, we compared the kidney weight of 41 consecutive cadaveric kidneys to donor BSA, dimensions measured with calipers at the time of transplantation, and dimensions supplied by the Organ Procurement Agency (OPA). Linear regression analysis was used with kidney weight as the dependent variable and BSA, kidney length, or kidney volume as the independent variable. Kidney length measured with calipers was also compared to kidney length supplied by the OPA. Kidney weight had the best correlation with kidney volume and kidney length determined by caliper measurements (r = 0.640 and 0.646, respectively). The regression analysis showed that the correlation of kidney weight with BSA was 0.487. The correlation of OPA-provided kidney length with kidney weights was poor (r = 0.410). The linear regression of caliper-measured kidney length versus OPA length yielded a slope of 0.360, instead of an ideal slope of 1. The assumption has been made that kidney weight or a surrogate of kidney weight has an excellent correlation with nephron mass. Some of the variability in studies that attempted to examine the effect of transplanted nephron mass on allograft outcome may be due to inaccurate estimates used for kidney weight. Our data suggest that surrogate measurements of kidney weight may not be accurate. We recommend that measured kidney weight should be used in studies examining the effect of donor renal mass on allograft outcomes.
The ideal ultrasound-assisted lipoplasty candidate differs little from the ideal candidate for traditional lipoplasty. This ideal candidate is within 20% of their ideal body weight (as determined by the insurance company statistics; i.e., 100 lbs for 5 feet in height, and 10 pounds for each inch above 5 feet). These patients were thought to be the only patients acceptable for lipoplasty when liposuction was first begun in the early 1980s. Innovative techniques, improved equipment, advances in superficial liposuction, syringe method, ultrasonic lipoplasty, external ultrasound assist, and other factors have served to expand the potential patient population greatly.
This study was designed to investigate the empirical tubular extraction rate (TER) of the normal renal function in childhood and then propose a new equation to obtain TER theoretically. The empirical TER was calculated using Russell's method for determination of single-sample plasma clearance and 99mTc-MAG3 in 40 patients with renal disease younger than 10 years of age who were classified as having normal renal function using diagnostic criteria defined by the Paediatric Task Group of EANM. First, we investigated the relationships of the empirical value of absolute TER to age, body weight, body surface area (BSA) and distribution volume. Next we investigated the relationships of the empirical value of BSA corrected TER to age, body weight, BSA and distribution volume. Linear relationship was indicated between the absolute TER and each body dimensional factors, especially regarding to BSA, its correlation coefficient was 0.90 (p value). The BSA-corrected TER showed a logarithmic relationship with BSA, but linear regression did not show any significant correlation. Therefore, it was thought that the normal value of TER could be calculated theoretically using the body surface area, and here we proposed the following linear regression equation: Theoretical TER (ml/min/1.73 m2) = (-39.8 + 257.2 x BSA)/BSA/1.73 The theoretical TER could be one of the reference values of the renal function in the period of the renal maturation.