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Viral persistence and immune dysfunction.

M B Oldstone
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Abstract

Viruses can persist for years without provoking an effective host immune response or otherwise causing the cell destruction characteristic of an acute viral infection. Clinically relevant principles, generalizable to many persistent viruses, are exemplified by measles and lymphocyte choriomeningitis viruses. The LCMV model indicates that viral persistence and the anergic state are reversible.

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AnimalsAntigen-Antibody ComplexHumansImmune ToleranceLymphocytic ChoriomeningitisMiceT-Lymphocytes, CytotoxicVirus DiseasesVirusesJournal ArticleReview

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BibTeXRIS

M B Oldstone. 1990-05-15. Viral persistence and immune dysfunction.. https://doi.org/10.1080/21548331.1990.11703948

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