Current concepts in autoimmunity.

C Boitard

doi:10.3109/02713689008999423

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Current concepts in autoimmunity.

C Boitard

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Abstract

Autoimmune diseases are subsequent to tissue damage mediated by an immune reaction directed toward autoantigens. Activation of CD4+ T cells reactive to carrier determinants on foreign antigenic complexes or autoreactive CD4+ T cells are central to the triggering of immune effector mechanisms. Transfer experiments in animals, demonstration of suppressor T cells, study of antigen-presenting cells--CD4+ T cells interaction, isolation of T cell clones and study of transgenic mice have recently brought new insight into the understanding of autoimmunity.

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Animals Antigen-Presenting Cells Autoimmunity CD4 Antigens Clone Cells Humans Immunization, Passive Mice Mice, Transgenic T-Lymphocytes T-Lymphocytes, Regulatory Journal Article Review

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C Boitard. 1990. Current concepts in autoimmunity.. https://doi.org/10.3109/02713689008999423

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