Study on the endothelin gene and its expression.

T Masaki; M Yanagisawa; A Inoue; S Kimura; K Goto

doi:10.1253/jcj.54.1221

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Study on the endothelin gene and its expression.

T Masaki·M Yanagisawa·A Inoue·S Kimura·K Goto

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Abstract

Endothelin (ET) is a potent vasoconstrictor peptide produced by vascular endothelial cells. Three distinct human endothelin genes were cloned and analysed. The results demonstrated that there were three distinct mRNAs for ET and that TPA-responsive element, mRNA stabilizing sequence, motifs for binding site of nuclear factor 1 and acute phase reactant regulatory elements were recognized in preproform ET-1 gene.

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Animals Cloning, Molecular Endothelins Gene Expression Humans Peptide Fragments RNA, Messenger Rats Receptors, Cell Surface Receptors, Endothelin Structure-Activity Relationship Swine Journal Article

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T Masaki, M Yanagisawa, A Inoue, S Kimura, K Goto. 1990. Study on the endothelin gene and its expression.. https://doi.org/10.1253/jcj.54.1221

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