[Hepatic triglyceride lipase].

G Simard; B Perret

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PubMed · 2188532

[Hepatic triglyceride lipase].

G Simard·B Perret

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Abstract

The post-heparin plasma contains two lipolytic enzymes. This review deals with the lesser known, hepatic triglyceride lipase. Like lipoprotein lipase, H-TGL is a glycoprotein and has an optimal pH of 8-9. But it does not require an activator protein and its activity is not inhibited by NaCl or protamine sulfate. Synthesized by the hepatocytes, H-TGL is located at the hepatic vascular endothelium. It catalyses the hydrolysis of a wide variety of lipid substrates including triacylglycerol and phospholipids. The function of the enzyme is still not fully known. H-TGL may function in the clearance of triglyceride rich lipoprotein remnants and in the catabolism of HDL.

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Amino Acid Sequence Animals Base Sequence Chemical Phenomena Chemistry, Physical Endothelium Humans Hydrolysis Lipase Lipoproteins, HDL Liver Molecular Sequence Data Rats Journal Article Review

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G Simard, B Perret. 1990. [Hepatic triglyceride lipase].. https://pubmed.ncbi.nlm.nih.gov/2188532/

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