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PubMed · 2190645

Human mononuclear phagocyte activation antigens.

R F Todd·I F Mizukami·S D Vinjamuri·R D Trochelman·W W Hancock·D Y Liu
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Abstract

Activation of mononuclear phagocytes causes changes in plasma membrane composition that include the expression of surface antigens and receptors. Monoclonal antibody technology has made it possible to identify and characterize newly expressed surface antigens. Among these "activation antigens" is a glycoprotein, Mo3, which (among hematopoietic cells) is selectively expressed by human mononuclear phagocytes that have been exposed to inflammatory factors in vitro and in vivo. Progress toward a functional and structural analysis of Mo3 is described.

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AnimalsAntigens, SurfaceHumansMacrophage ActivationMonocytesJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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R F Todd, I F Mizukami, S D Vinjamuri, R D Trochelman, W W Hancock, D Y Liu. 1990. Human mononuclear phagocyte activation antigens.. https://pubmed.ncbi.nlm.nih.gov/2190645/

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