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PubMed · 219691

Feedback-controlled dextrose infusion during surgical management of insulinomas.

J H Karam·M Lorenzi·C W Young·A D Burns·P R Prosser·G M Grodsky·M Galante·P H Forsham
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Abstract

Through the use of a feedback-controlled dextrose infusion system, we obtained continuous monitoring of the blood glucose level in a patient undergoing surgery for multiple pancreatic beta-cell tumors. In addition, this device infused dextrose at variable rates to maintain a predetermined euglycemic level of 90 mg/dl. Before locating the source of excessive insulin production, the maximum dextrose infusion rate of 400 mg/min was required; but after extirpation of multiple insulinomas, the dextrose-infusion rate declined whereas the blood glucose level rose above the preselected level. These results emphasize the usefulness of a monitoring and infusion system not only in protecting the patient from the hazard of hypoglycemia under anesthesia but also as an aid in determining whether all insulin-secreting tumors have been removed.

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Adenoma, Islet CellAgedBlood GlucoseFeedbackFemaleGlucoseHumansInfusions, ParenteralMonitoring, PhysiologicPancreatic NeoplasmsCase ReportsJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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J H Karam, M Lorenzi, C W Young, A D Burns, P R Prosser, G M Grodsky, M Galante, P H Forsham. 1979. Feedback-controlled dextrose infusion during surgical management of insulinomas.. https://doi.org/10.1016/0002-9343(79)91183-5

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