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PubMed · 2217634

[Preventive measures in bronchial provocation tests].

A Gruden-Gros
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Abstract

The author's own experiences together with the data from the literature are presented for application the bronchial provocation tests in the hospital and in out-patient's department for pulmonary disease. Contraindications and side effects in testing the nonspecific provocative agents are presented (metacholine, histamine, carbachol), in specific provocative agents as well as in exercise testing. These tests are relatively harmless if the preventive measures are taken into account.

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A Gruden-Gros. [Preventive measures in bronchial provocation tests].. https://pubmed.ncbi.nlm.nih.gov/2217634/

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Capsaicin cough sensitivity in bronchiectasis.

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Bronchial Provocation Tests↗
PubMed2006

[Comparison of unspecific bronchial provocation during controlled and spontaneous inhalation].

Using controlled breathing patterns during inhalation of drugs is characterized by a high dose reproducibility which may be of advantage for bronchial provocation testing. In this study 30 healthy subjects with an anamnesis of atopy underwent in a randomized cross-over design bronchial provocation testing with methacholine either with the Viasys-Jäger-APS system or with controlled inhalations (AKITA-System) (controlled inhalation volume and flow). Measured was the frequency of positive test results. Positive test results were defined by a 20 % decline of FEV (1) or a 100 % increase of specific airway resistance (sRaw). There were no significant differences in the prevalence of positive test results obtained with both techniques: APS-FEV (1) : 8, AKITA-FEV (1) : 9; APS-sRaw: 18, AKITA-sRaw: 17. More subjects showed a 100 % increase of sRaw as compared to a 20 % decrease of FEV (1), which may be interesting in order to understand differences in the diagnostic information given by both parameters. However, there were some discrepancies: only in 25 of 30 cases (sRaw: 21 of 30 cases) the results (positive or negative) agreed between both techniques. Although the two techniques for bronchial provocation test showed some discrepancies, these data suggest that controlled inhalations may be an alternative to the APS-system.

Bronchial Provocation Tests↗