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PubMed · 2218965

[Pharmacogenetics for the practicing physician].

M Bargetzi
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Abstract

An important source of interindividual differences in drug action are inherited differences in the pharmacokinetics and pharmacodynamics of many drugs. Besides some well-known but rarely occurring examples of unusual drug action, the inherited variations of drug metabolism are of particular clinical importance, as a relationship between the defect of metabolism and the effects and toxicity of the drugs involved has been observed. Recent investigations were able to elucidate many of the molecular mechanisms responsible for these genetic defects.

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HumansMetabolism, Inborn ErrorsPharmacogeneticsPharmacokineticsPharmacologyEnglish AbstractJournal Article

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M Bargetzi. 1990. [Pharmacogenetics for the practicing physician].. https://pubmed.ncbi.nlm.nih.gov/2218965/

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