PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 2228915

Benhaven's residential program.

L R Simonson·S M Simonson·F R Volkmar
View original source ↗Export metadata ↓

Abstract

Benhaven, a residential program of group homes providing intensive programming for autistic and neurologically impaired children, is described. Its major program factors of administration and management, treatment, support services, and family and community involvement are presented in detail. Benhaven's mission as an educational placement for preparing residents to function in the least restrictive environment on their way to future living situations is stressed.

Explore related subjects

Autistic DisorderBehavior TherapyBrain Damage, ChronicChildCombined Modality TherapyFamily TherapyGroup HomesHumansPatient Care TeamResidential TreatmentSocial AdjustmentSocial EnvironmentJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

L R Simonson, S M Simonson, F R Volkmar. 1990. Benhaven's residential program.. https://doi.org/10.1007/bf02206545

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2003

A genomewide screen of 345 families for autism-susceptibility loci.

We previously reported a genomewide scan to identify autism-susceptibility loci in 110 multiplex families, showing suggestive evidence (P <.01) for linkage to autism-spectrum disorders (ASD) on chromosomes 5, 8, 16, 19, and X and showing nominal evidence (P <.05) on several additional chromosomes (2, 3, 4, 10, 11, 12, 15, 18, and 20). In this follow-up analysis we have increased the sample size threefold, while holding the study design constant, so that we now report 345 multiplex families, each with at least two siblings affected with autism or ASD phenotype. Along with 235 new multiplex families, 73 new microsatellite markers were also added in 10 regions, thereby increasing the marker density at these strategic locations from 10 cM to approximately 2 cM and bringing the total number of markers to 408 over the entire genome. Multipoint maximum LOD scores (MLS) obtained from affected-sib-pair analysis of all 345 families yielded suggestive evidence for linkage on chromosomes 17, 5, 11, 4, and 8 (listed in order by MLS) (P <.01). The most significant findings were an MLS of 2.83 (P =.00029) on chromosome 17q, near the serotonin transporter (5-hydroxytryptamine transporter [5-HTT]), and an MLS of 2.54 (P =.00059) on 5p. The present follow-up genome scan, which used a consistent research design across studies and examined the largest ASD sample collection reported to date, gave either equivalent or marginally increased evidence for linkage at several chromosomal regions implicated in our previous scan but eliminated evidence for linkage at other regions.

Autistic Disorder↗
PubMed2003

Molecular genetics of autism spectrum disorders.

Autistic disorder belongs to a broad spectrum of pervasive developmental disorders. Autism is a clinically and genetically heterogeneous condition. It is characterized by impairment in a broad range of social interactions, communication, and repetitive patterns of behavior and interest. Although the exact etiology of the condition is not known, family and twin studies strongly support genetic factors in autism. Genome-wide scans suggest several susceptibility loci that may contain one or more predisposing genes. However, no such genes have been identified so far that predispose patients to autism. The condition is over 90% heritable, but the mode of inheritance is not clear. Moreover, it does not seem to be a single gene disorder. There is no cure for autism. Individualized structured education, family support services, and antipsychotic drugs are recommended. These may alleviate some behavioral problems. The identification of autism genes, an understanding of the neurobiology of the condition, and additional clinical studies may help to develop pharmacological interventions in the future.

Autistic Disorder↗