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PubMed · 2241877

[Bone replacement using demineralized allogeneic bone in animal experiments].

N Schwarz·H Redl·G Schlag
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Abstract

The implantation of bone matrix in muscle bag or trepanation defects of rats with greatest reproducibility will induce osteogenesis and defect healing. The phenomenon of osteo-induction was possible to obtain only in first steps in higher developed mammals. Investigations in nude rats have shown a clear difference in biologic reaction on the matrix of various species. The osteo-regeneration in replacement weak defect of ulnar bone in dogs showed a massive greater reactivity of autogenous spongiosa, whereas bank spongiosa and bone matrix produced not more new bone as the control. An increase of osteoinductive matrix potency is a supposition for practical use in case of severe bone defects.

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AnimalsBone MatrixBone TransplantationMusclesOsteogenesisRatsRats, Inbred StrainsWound HealingEnglish AbstractJournal Article

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N Schwarz, H Redl, G Schlag. 1990. [Bone replacement using demineralized allogeneic bone in animal experiments].. https://pubmed.ncbi.nlm.nih.gov/2241877/

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