PubMed · 2266352
Gall-bladder perforation after long-term dapsone therapy.
Abstract
A 65-year-old man on maintenance dapsone therapy for dermatitis herpetiformis for 30 years was admitted to hospital with acute abdominal pain and vomiting. Investigations revealed a Heinz body haemolytic anaemia. Worsening symptoms prompted an emergency laparotomy that revealed a perforated gall bladder with pigmented biliary calculi. In previous reviews of the haematological abnormalities associated with dapsone therapy, life-threatening cholecystitis has not been described.
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A M Choy, C C Lang. 1990. Gall-bladder perforation after long-term dapsone therapy.. https://doi.org/10.1111/j.1365-2796.1990.tb00254.x
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