Naproxen parenteral formulation studies.

K S Peswani; J K Lalla

PubMed · 2277322

Naproxen parenteral formulation studies.

Abstract

Naproxen sodium has been formulated in a parenteral dosage form. After a series of experiments involving solubility, pH, and excipient compatibility using Placket Burman experimental design, the formulation has been finalized. The accelerated stability studies on samples stored at high temperatures projected the shelf life to be 4.2 years. Toxicological, therapeutic efficacy, and other aspects of this formulation are being reported separately.

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Chemistry, Pharmaceutical Drug Stability Hot Temperature Hydrogen-Ion Concentration Infusions, Parenteral Light Naproxen Oxygen Solubility Journal Article

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K S Peswani, J K Lalla. Naproxen parenteral formulation studies.. https://pubmed.ncbi.nlm.nih.gov/2277322/

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