[In vitro drug-resistance decrease of ovarian cancer cells].

S M Lu

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PubMed · 2282862

[In vitro drug-resistance decrease of ovarian cancer cells].

S M Lu

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Abstract

A chemosensitivity test for ovarian cancer using tritiated thymidine incorporation assay was carried out. A dose-response relationship was observed for cis-platinum and an 5-fold increase of concentration converted the drug resistant tumor into a drug-sensitive one. Verapamil was found to enhance the cytotoxic effect of vincristine against ovarian cancer cells. It is suggested that combination of vincristine with verapamil may be helpful in treating some vincristine-resistant cases.

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Cisplatin Cystadenocarcinoma Drug Resistance Drug Screening Assays, Antitumor Drug Synergism Female Humans Ovarian Neoplasms Tumor Cells, Cultured Verapamil Vincristine English Abstract Journal Article

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S M Lu. 1990. [In vitro drug-resistance decrease of ovarian cancer cells].. https://pubmed.ncbi.nlm.nih.gov/2282862/

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