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PubMed · 2349458

[Cat-scratch disease].

J Schädelin
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Abstract

Cat scratch disease is a self-limited but chronic lymphadenitis which has acquired new interest by the description of a responsible pathogen, an intracellularly located gram-negative rod. Due to its low pathogenicity for laboratory animals, the definite proof for causality is still lacking. Severe systemic courses, mainly in immune suppressed patients, can however be identified more positively by detection of this pathogen. A routine diagnostic test is likely to be developed in the near future and therapeutic guidelines for the minority of severe, progressive forms may be drawn up.

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Cat-Scratch DiseaseGram-Negative BacteriaHumansImmunologic Deficiency SyndromesMicrobial Sensitivity TestsEnglish AbstractJournal Article

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J Schädelin. 1990-05-19. [Cat-scratch disease].. https://pubmed.ncbi.nlm.nih.gov/2349458/

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PubMed1996

[Cat scratch disease. Atypical forms].

First described by Robert Debré in 1950, cat scratch disease, usually observed in children and young adults (80% of the case occur in subjects under 18), is the principal cause of chronic benign lymph node enlargement. The Centers for Disease Control at Atlanta currently recognize Afipia felis and Rochalimaea henselae as the causal agents of cat scratch disease. Cats transmit the disease to humans by skin scratches or by licking open wounds. The bacilli can also be transmitted by dogs, monkeys, squirels or inert objects. The contaminating cats are usually young. There is no interhuman transmission. There are several uncommon manifestations of cat scratch disease which may misguide diagnosis. In atypical forms, the positive diagnosis of this benign disease can only be confirmed by serology or molecular biology techniques. In order to reduce the duration of the disease, antibiotic treatment is recommended in forms with systemic involvement and in atypical forms although there has been no proof of efficacy.

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PubMed1996

[Cat scratch disease in immunocompetent children].

First cause of chronic benign lymphadenopathy, cat scratch disease occurs mainly in children and young adults. The nature of its bacterial agents is not definitely established, but Atlanta's CDC actually considers Afipia felis and Rochalimaea hensaela as the agents of the disease. It usually presents as chronic adenitis but there are severe forms of the disease with systemic manifestation. In such forms, new techniques such as serology and molecular biology are particularly useful for the diagnosis. The prognosis is always excellent and an antibiotic treatment is only recommended for systemic forms to reduce the duration of the disease.

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