Differences between human and rabbit transferrins.

J V Princiotto; E J Zapolski

doi:10.1016/0304-4165(78)90123-x

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Differences between human and rabbit transferrins.

J V Princiotto·E J Zapolski

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Abstract

Rabbit reticulocyte incorporation of iron from rabbit transferrin was independent of transferrin iron saturation but uptake from human transferrin was saturation dependent. Unlike human transferrin, rabbit transferrin does not surrender its iron from any unique preferred iron-binding site and can be described as functionally homogeneic. The two proteins also differ in their acid-base iron-binding properties. One human transferrin iron binding site retains an ability to bind iron at somewhat acid pH but this property is not shared by rabbit transferrin.

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Animals Binding Sites Humans Hydrogen-Ion Concentration In Vitro Techniques Iron Kinetics Rabbits Reticulocytes Species Specificity Transferrin Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

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J V Princiotto, E J Zapolski. 1978-02-13. Differences between human and rabbit transferrins.. https://doi.org/10.1016/0304-4165(78)90123-x

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