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Apolipoprotein E: receptor binding properties.

K H Weisgraber·T L Innerarity·S C Rall·R W Mahley
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Abstract

The E apoprotein plays a central role in lipoprotein metabolism. It is a key protein determinant responsible for the recognition of lipoproteins by specific lipoprotein receptors. Structure-function studies are providing insights into the normal function of this apoprotein in cholesterol homeostasis and into the clinical abnormalities resulting from the occurrence of specific mutants.

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Antibodies, MonoclonalApolipoproteins EBinding SitesBinding, CompetitiveEpitopesHumansHyperlipoproteinemia Type IIIIsoelectric PointPeptide FragmentsReceptors, Cell SurfaceReceptors, LDLReceptors, LipoproteinStructure-Activity RelationshipJournal Article

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K H Weisgraber, T L Innerarity, S C Rall, R W Mahley. 1985. Apolipoprotein E: receptor binding properties.. https://doi.org/10.1007/978-1-4613-2459-1_13

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