PubMed · 2436465
Prenatal testing for maternal serum alpha-fetoprotein.
Abstract
The maternal serum alpha-fetoprotein level should be measured in all pregnant women at 16 to 20 weeks of gestation. Elevated alpha-fetoprotein levels require evaluation by ultrasonography and, sometimes, amniocentesis to detect neural tube defects. Low alpha-fetoprotein levels may be associated with chromosomal anomalies and should be evaluated with amniocentesis. Alpha-fetoprotein testing is cost-effective, and medicolegal liability makes it imperative to offer this screening test to all pregnant women.
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E J Schwager, B D Weiss. 1987. Prenatal testing for maternal serum alpha-fetoprotein.. https://pubmed.ncbi.nlm.nih.gov/2436465/
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