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PubMed · 2443997

Protein C functional assay using snake venom activator.

I V Nathan·H Ping·M M Pradhan
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Abstract

We report a functional assay of Protein C on whole plasma using a snake venom called Protac-C. This method is simple, avoids absorption-elution techniques. Also this method can be adopted to a microtitre plate system testing of large number of samples. Functional levels by this test correlated well with the antigenic levels (r = .8) measured by ELISA. Protein C functional and antigenic values in 58 healthy volunteers were 82% and 95.5% respectively. The warfarinized samples showed a lower mean.

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Chromogenic CompoundsEnzyme ActivationEnzyme-Linked Immunosorbent AssayEpitopesHumansIntercellular Signaling Peptides and ProteinsMethodsPeptidesProtein CTime FactorsComparative StudyJournal Article

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I V Nathan, H Ping, M M Pradhan. 1987-07-01. Protein C functional assay using snake venom activator.. https://doi.org/10.1016/0049-3848(87)90243-x

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