CD5 positive B lymphocytes: a link between autoimmunity and B-cell oncogenesis.

R Bataille; B Klein

PubMed · 2460021

CD5 positive B lymphocytes: a link between autoimmunity and B-cell oncogenesis.

Abstract

A strong relationship exists between autoimmunity and B-cell oncogenesis. Recent evidence indicates that CD5-positive B-cells are involved in both the production of (germ-line encoded) autoantibodies and the clonal B-cell expansions. Thus, this special B-cell subset represents a strong link between autoimmune state and B-cell malignancies. Immunotherapy of both autoimmune diseases and B-cell malignancies. Immunotherapy of both autoimmune diseases and B-cell cancers should consider the relationship between both processes.

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Animals Antigens, Differentiation Autoimmune Diseases B-Lymphocytes CD5 Antigens Humans Lymphoma Neoplasms Journal Article Research Support, Non-U.S. Gov't Review

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R Bataille, B Klein. CD5 positive B lymphocytes: a link between autoimmunity and B-cell oncogenesis.. https://pubmed.ncbi.nlm.nih.gov/2460021/

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