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Grooming behavior induced by substance P.

T B Van Wimersma Greidanus·C Maigret
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Abstract

The intracerebroventricular (i.c.v.) administration of substance P elicits in rats an excessive grooming that is characterized by body grooming, anogenital grooming and scratching. The total grooming scores displayed by rats treated with substance P hardly exceeded 23% of the theoretical maximal grooming score. Substance P-induced excessive grooming was suppressed by pretreatment with naloxone, haloperidol on neurotensin. It is concluded that substance P induces excessive grooming with a pattern different from that of grooming elicited by other peptides.

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AnimalsDose-Response Relationship, DrugGroomingHaloperidolInjections, IntraventricularMaleNaloxoneNeurotensinRatsRats, Inbred StrainsSubstance PJournal Article

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BibTeXRIS

T B Van Wimersma Greidanus, C Maigret. 1988-09-13. Grooming behavior induced by substance P.. https://doi.org/10.1016/0014-2999(88)90102-1

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