Interleukin 1.

D N Sauder

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PubMed · 2469399

Interleukin 1.

D N Sauder

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Abstract

The last decade has witnessed a remarkable expansion in the understanding of the skin as an immunologic organ. A prime example of this is the discovery that keratinocytes can synthesize and secrete immunoregulatory and proinflammatory glycoproteins termed cytokines. Initial studies focused on interleukin 1-like molecules produced by keratinocytes, initially termed epidermal cell-derived thymocyte activating factor (ETAF). It is now clear that the functional activities described by the term ETAF are composed mainly of interleukin 1 alpha and interleukin 1 beta, although other epidermal cytokines may contribute to the biologic activity. The biologic properties of interleukin 1 are the basis of this review.

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Animals Epidermis Humans Inflammation Interleukin-1 Keratins Lymphocytes Molecular Structure Tumor Necrosis Factor-alpha Journal Article Review

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D N Sauder. 1989. Interleukin 1.. https://pubmed.ncbi.nlm.nih.gov/2469399/

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