PubMed · 2473531
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J Ruiz, V Danel. 1989. [Volume expanders. Colloidal plasma substitutes].. https://pubmed.ncbi.nlm.nih.gov/2473531/
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Linear compartmental models are used to describe the disposition of radio-labelled compounds in regions of interest in the mammalian body, based on a time sequence of measurements from a positron emission tomograph (PET). In this paper we show how closed form solutions for the model equations have been incorporated into a computer program for simulation and parameter estimation. A typical PET data example is included to illustrate the implementation and compare the closed form method with a numerical ode solution method.
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