Stage-specific gene expression in early chick embryo.

N Zagris; D Matthopoulos

doi:10.1002/dvg.1020100409

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Stage-specific gene expression in early chick embryo.

N Zagris·D Matthopoulos

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Abstract

Inhibition of DNA replication by aphidicolin in the chick morula interferes with its progression to a normal blastula and prevents induction of the first morphogenetic cell movements of primitive streak formation. Embryos in aphidicolin synthesize some polypeptides typical of blastula but do not display all the characteristic features of morula to blastula transition. Inhibition of DNA replication interferes with the sequential synthesis of maternally coded polypeptides and with the activation of the embryonic genome in the chick embryo.

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Animals Aphidicolin Blastocyst Cell Aggregation Cell Division Chick Embryo Cleavage Stage, Ovum DNA Polymerase II DNA Replication Diterpenes Electrophoresis, Polyacrylamide Gel Gene Expression Regulation Histocytochemistry Morphogenesis Morula Protein Biosynthesis Journal Article Research Support, Non-U.S. Gov't

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N Zagris, D Matthopoulos. 1989. Stage-specific gene expression in early chick embryo.. https://doi.org/10.1002/dvg.1020100409

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