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PubMed · 2509496

The endogenous pyrogens in host-defense interactions.

C A Dinarello
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Abstract

Soluble factors produced by activated macrophages serve to marshal host defenses against infection, injury, or inflammation, but they may also cause chronic inflammation or even lethal shock. Suppressing or enhancing such cytokine functions has important therapeutic potential in, respectively, chronic inflammatory and immunologically deficient states.

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AnimalsCell MembraneFatty Acids, Omega-3FeverFish OilsHumansImmunologic Deficiency SyndromesInflammationInterleukin-1Interleukin-6Leukocytes, MononuclearMacrophage ActivationPyrogensRabbitsTumor Necrosis Factor-alphaComparative StudyJournal ArticleReview

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C A Dinarello. 1989-11-15. The endogenous pyrogens in host-defense interactions.. https://doi.org/10.1080/21548331.1989.11703813

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