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PubMed · 2515643

Slide culture sensitivity tests.

J M Dickinson·B W Allen·D A Mitchison
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Abstract

A new method for slide culture sensitivity tests of Mycobacterium tuberculosis is described in which smear-positive sputum spread on slides is incubated without prior decontamination in a selective lysed human blood medium. Results are available 7 days after setting up the tests and are particularly useful for guiding the treatment of smear-positive patients with a long history of unsuccessful chemotherapy. Drug concentrations and definitions of resistance are suggested for tests against isoniazid, streptomycin, PAS, rifampicin ethambutol and ethionamide. A good correlation was seen between the results of these tests and those of standard indirect sensitivity tests.

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Antitubercular AgentsBacteriological TechniquesCulture MediaHumansMicrobial Sensitivity TestsMycobacterium tuberculosisSputumJournal Article

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J M Dickinson, B W Allen, D A Mitchison. 1989. Slide culture sensitivity tests.. https://doi.org/10.1016/0041-3879(89)90035-4

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