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Catecholamine melanins. Structural changes induced by copper ions.

K B Stepień·J P Dworzański·B Bilińska·M Porebska-Budny·A M Hollek·T Wilczok
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Abstract

Melanins synthesized from adrenaline and dopamine in the presence or absence of copper ions were characterized by pyrolysis-gas chromatography-mass spectrometry and by IR and ESR methods. It was shown that Cu2+ are able to induce changes in the melanin structure. Melanins obtained from adrenaline-Cu2+ and dopamine-Cu2+ complexes are composed mainly from monomeric units of the indole type. Melanins synthesized from these catecholamines without Cu2+ contain additionally large amounts of unindolized monomeric units. The structure differences in both types of melanins are reflected in their sorptive abilities and spectroscopic characteristics.

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ChloroquineCopperDopamineElectron Spin Resonance SpectroscopyEpinephrineGas Chromatography-Mass SpectrometryIn Vitro TechniquesMelaninsMolecular StructureSpectrophotometry, InfraredComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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K B Stepień, J P Dworzański, B Bilińska, M Porebska-Budny, A M Hollek, T Wilczok. 1989-07-27. Catecholamine melanins. Structural changes induced by copper ions.. https://doi.org/10.1016/0167-4838(89)90134-9

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