Enterotoxin induced diarrhoea--an update.

G B Nair; S C Pal

PubMed · 2554547

Enterotoxin induced diarrhoea--an update.

Abstract

The pathogenic personality or the criteria required to be a successful pathogen, of enteric bacteria includes, among others, the ability to produce potent proteins which by different intracellular mechanisms elicit what we overtly see as diarrhoea. Enteropathogens belonging to several genera like Vibrio, Escherichia, Shigella, Salmonella, Campylobacter, Aeromonas and Yersinia include species capable of elaborating strikingly similar exotoxins which seem to share common mechanisms of action involving specific receptor binding, internalization of the toxin followed by interaction with an intracellular target. It is now clear that there are several families of structurally, functionally and immunologically identical bacterial enterotoxins. In this communication, we have reviewed the recent developments on the various families of structurally homologous and antigenically cross reacting enteric toxins.

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Bacterial Proteins Bacterial Toxins Cholera Toxin Cytotoxins Diarrhea Enterotoxins Guanylate Cyclase Humans Receptors, Cell Surface Receptors, Enterotoxin Receptors, Guanylate Cyclase-Coupled Receptors, Peptide Shiga Toxins Journal Article Review

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G B Nair, S C Pal. Enterotoxin induced diarrhoea--an update.. https://pubmed.ncbi.nlm.nih.gov/2554547/

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