PubMed · 2560919
[Signal transmission using second messengers].
Abstract
Intercellular communication needs signal molecules (hormones, neurotransmitters, growth factors) emitted by a cell and recognized by targets. A widespread mechanism of cellular action of these molecules involves a membrane receptor, a GTP-dependent coupling protein, an effector which modulates the intracellular concentration of a second messenger (cAMP, cGMP, inositol triphosphate, Ca++), and a target for final effect of this second messenger (kinases, channel). Hormonal systems and visual processes in vertebrates rod outer segments are the best known examples of this mechanism; they are taken here to illustrate the state of knowledge of the interactions between the actors of the transductional enzymatic cascades.
Explore related subjects
Keep this discovery
Explore connections, maps & timelines
C Pfister. 1989. [Signal transmission using second messengers].. https://pubmed.ncbi.nlm.nih.gov/2560919/
Cite the original work for its findings. Save a collection to share your selection of sources.