Interrelationship between cyclic AMP level and chondrogenesis in vitro.

C Hadházy; M B László

PubMed · 2561389

Interrelationship between cyclic AMP level and chondrogenesis in vitro.

Abstract

A consistent chondrogenesis takes place in micro-mass cultures of stage 23-24 chicken limb bud mesenchymal cells. In these cultures a short, marked elevation of cAMP level was detected at the time of the onset of cartilage phenotype expression. On the other hand, exogeneous glycosaminoglycans which inhibited chondrogenesis caused a reduction in the cAMP level of the cells. These correlations between cAMP level and phenotypic characteristics suggest that, among other things required in chondrogenesis, cAMP level may be a prominent factor.

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Animals Cartilage Cells, Cultured Chick Embryo Cyclic AMP Extremities Glycosaminoglycans Mesoderm Morphogenesis Journal Article

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C Hadházy, M B László. Interrelationship between cyclic AMP level and chondrogenesis in vitro.. https://pubmed.ncbi.nlm.nih.gov/2561389/

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