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Is oxytocin present in platelets?

F M Helmerhorst·A M van den Boogaard·N Naaktgeboren·R M Lequin
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Abstract

For arginine-vasopressin (AVP) it has been suggested that about 90% of the total amount present in peripheral blood is platelet-membrane bound. Oxytocin (OT) and AVP are nonapeptides which are similar in many respects. We investigated the possibility that OT might be found in platelet-rich plasma samples from patients undergoing ovarian super-stimulation for in-vitro fertilization purposes. These plasma samples were treated with acid repeated freezing/thawing and sonification in an attempt to solubilize or expose the possible bound OT. No differences between OT concentrations in platelet-rich or -poor plasma samples were found. We conclude that plasma OT is not bound or confined to platelets.

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Blood PlateletsCell MembraneFemaleHumansOxytocinRadioimmunoassayJournal Article

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BibTeXRIS

F M Helmerhorst, A M van den Boogaard, N Naaktgeboren, R M Lequin. 1989. Is oxytocin present in platelets?. https://doi.org/10.3109/09513598909152307

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