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PubMed · 2589864

Dermal thymus. A light microscopic and immunohistochemical study.

R J Barr·D J Santa Cruz·R M Pearl
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Abstract

Two rare cases of distinctive thymic remnants occurring in the skin are described. The lesions were present at birth, and involved the side of the neck. One child had a complete cleft lip and palate. The other had multiple congenital anomalies consistent with a rare syndrome entitled branchio-oculo-facial syndrome. Microscopically, lobular foci were present in the dermis and consistent with both prethymic and thymic remnants. Immunohistochemical studies using antibodies to T cells and B cells showed a distribution similar to that seen in normal thymus. Dermal thymus appears to be a distinct entity and may be associated with other faciobranchial defects.

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Abnormalities, MultipleChild, PreschoolChoristomaFemaleHumansNeckSkin NeoplasmsThymus GlandCase ReportsJournal Article

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R J Barr, D J Santa Cruz, R M Pearl. 1989. Dermal thymus. A light microscopic and immunohistochemical study.. https://doi.org/10.1001/archderm.125.12.1681

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