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Computer model of ventricular interaction during left ventricular circulatory support.

J C Woodard·D J Farrar·E Chow·W P Santamore·D Burkhoff·J D Hill
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Abstract

The authors used a computer model of the heart and circulation to test the hypothesis that anatomic ventricular interactions are responsible for the observed instances of right ventricular failure during use of a left ventricular assist device. The model predicts that left ventricular pressure-unloading with a LVAD, in the presence of isolated systolic interaction, results in impairment of RV function, whereas with isolated diastolic interaction, RV function is improved. Due to competition between these two interactions, there is a negligible overall effect of ventricular anatomic interactions in determining right ventricular function in the normal heart.

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Computer SimulationDiastoleHeart FailureHeart VentriclesHeart-Assist DevicesHemodynamicsHumansModels, CardiovascularMyocardial ContractionStroke VolumeSystoleJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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BibTeXRIS

J C Woodard, D J Farrar, E Chow, W P Santamore, D Burkhoff, J D Hill. Computer model of ventricular interaction during left ventricular circulatory support.. https://doi.org/10.1097/00002480-198907000-00086

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