Leukoencephalopathy after cisplatin therapy.

W Brück; E Heise; R L Friede

PubMed · 2620478

Leukoencephalopathy after cisplatin therapy.

Abstract

Cisplatin is a neurotoxic chemotherapeutic agent known to cause sensory peripheral neuropathy or ototoxicity. We report a patient with an oropharynx carcinoma who developed a multifocal, necrotizing leukoencephalopathy after cisplatin treatment. This indicates that cisplatin can induce, similar to other chemotherapeutic agents, demyelinating, necrotizing lesions in the white matter of the cerebrum.

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Carcinoma, Squamous Cell Cisplatin Female Frontal Lobe Humans Leukoencephalopathy, Progressive Multifocal Middle Aged Necrosis Occipital Lobe Oropharyngeal Neoplasms Parietal Lobe Case Reports Journal Article

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W Brück, E Heise, R L Friede. Leukoencephalopathy after cisplatin therapy.. https://pubmed.ncbi.nlm.nih.gov/2620478/

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