Age and membrane fluidity.

R Wahnon; S Mokady; U Cogan

doi:10.1016/0047-6374(89)90103-6

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Age and membrane fluidity.

R Wahnon·S Mokady·U Cogan

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Abstract

Male rats aged 1, 9 and 19 months were used to study changes in membrane fluidity with age, employing the fluorescence polarization technique with 1,6-diphenyl-1,3,5-hexatriene (DPH) as the fluorescent probe. The intestinal microvillus membranes derived from the 19-month-old rats were found to possess lower fluidity than that observed with the membranes derived from the younger animals. The decrease in fluidity with age was also reflected in a corresponding increase in the gel-to-liquid crystalline transition temperature. Only small insignificant changes with age, were observed in the fluidity of the red blood cell membrane.

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Aging Animals Cell Membrane Erythrocyte Membrane Intestinal Mucosa Male Membrane Fluidity Rats Journal Article

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R Wahnon, S Mokady, U Cogan. 1989. Age and membrane fluidity.. https://doi.org/10.1016/0047-6374(89)90103-6

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