Synaptic structural plasticity: role of synaptic shape.

E J Markus; T L Petit

doi:10.1002/syn.890030102

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Synaptic structural plasticity: role of synaptic shape.

E J Markus·T L Petit

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Abstract

Recent research has indicated that synaptic curvature is an important and potentially critical plastic feature of the synapse. Alterations in synaptic shape are related to synaptic function, being found both during maturation and in adulthood following neuronal activation. In this paper we review the evidence supporting synaptic shape as a plastic feature of synaptic structure. We also propose several mechanisms which might underlie these changes in shape. Finally, we suggest the possible functional role of alterations in synaptic curvature, including its potential in altering synaptic transmission efficacy.

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Aging Animals Central Nervous System Microscopy, Electron Neuronal Plasticity Synapses Journal Article Research Support, Non-U.S. Gov't Review

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E J Markus, T L Petit. 1989. Synaptic structural plasticity: role of synaptic shape.. https://doi.org/10.1002/syn.890030102

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