Randomized clinical trials: issues for researchers.

M S Fetter; S L Feetham; K D'Apolito; B A Chaze; A Fink; B B Frink; M K Hougart; C H Rushton

PubMed · 2648334

Randomized clinical trials: issues for researchers.

M S Fetter·S L Feetham·K D'Apolito·B A Chaze·A Fink·B B Frink·M K Hougart·C H Rushton

Abstract

The clinical trial is a randomized prospective study of human subjects in which the effectiveness of an intervention is compared against a control. Such a trial is considered to be a critical test of an innovative therapy. Trials require careful design and planning to be scientifically valid and clinically pertinent. In this review the clinical trial and its role in research are defined, and major ethical, methodological, and feasibility issues associated with trial design and organization are described.

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Clinical Trials as Topic Ethics, Professional Feasibility Studies Random Allocation Journal Article Research Support, U.S. Gov't, P.H.S.Review

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M S Fetter, S L Feetham, K D'Apolito, B A Chaze, A Fink, B B Frink, M K Hougart, C H Rushton. Randomized clinical trials: issues for researchers.. https://pubmed.ncbi.nlm.nih.gov/2648334/

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