[Knowing pemphigus].

Abstract

The classification, pathogenesis, clinical features and treatment of pemphigus are examined with emphasis' on the histopathological similarities of the elementary intraepithelial lesion and the histotopographical differences at epithelial level that differentiate the various types of pemphigus. In a detailed review of the pathogenesis of the condition, the circumstances propitious for the onset of pemphigus are identified as an HLA phenotype and the autoantigenic denaturation of the glycocalyx. The condition is described as vesicolobullous and is differentiated from similar bullous and non-bullous dermatoses. The most significant pictures of oral pemphigus are specified as are the basic elements of general and local treatment.