Secondary structural complementarity between DNA and proteins.

G M Church; J L Sussman; S H Kim

doi:10.1073/pnas.74.4.1458

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Secondary structural complementarity between DNA and proteins.

G M Church·J L Sussman·S H Kim

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Abstract

A model for the complex between double-stranded DNA and a beta-ribbon (a two-stranded antiparallel beta-sheet) of proteins is proposed as one of the possible modes of structural recognition between DNA and proteins. In this model, the contact occurs on the narrow groove of DNA, and the symmetry elements as well as the repeat distances of DNA and the beta-ribbon coincide, thus providing favorable complementary contacts.

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Binding Sites DNA Hydrogen Bonding Models, Molecular Nucleic Acid Conformation Protein Binding Protein Conformation Proteins Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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G M Church, J L Sussman, S H Kim. 1977. Secondary structural complementarity between DNA and proteins.. https://doi.org/10.1073/pnas.74.4.1458

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