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PubMed · 2662876

[Osteocalcin or bone GLA-protein].

R Mariani·S Altarès·E Bérard
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Abstract

Osteocalcin or GLA bone protein, the most abundant of non-collagen proteins in bone, is produced only by osteoblasts. Synthesis is enhanced by the active form of vitamin D. Most of the osteocalcin produced combines with hydroxyapatite crystals, but a small proportion is circulated in the bloodstream and eliminated by the kidneys. Because bone resorption and bone formation are closely linked, serum osteocalcin is a specific and reliable marker of bone tissue activity.

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R Mariani, S Altarès, E Bérard. 1989. [Osteocalcin or bone GLA-protein].. https://pubmed.ncbi.nlm.nih.gov/2662876/

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