PubMed · 2674023
Computer simulation for teaching membrane potential fundamentals.
Abstract
A computer simulation of membrane potential generation is presented. It allows the user to vary the intra and extracellular concentrations of sodium, potassium and chloride ions (Na+, K+ and Cl-), and determine the membrane potential and the equilibrium potential for each ion. The permeability coefficients for the ionic species considered, and the temperature may also be changed at will. Concentration-potential curves may be obtained at any time. The user may also select a voltage clamp option, which allows him to impose a certain membrane potential value, and study the resulting driving force for each ion. The use of the program in general physiology courses has shown it to be a useful aid for teaching the principles of membrane potential generation.
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E Soto. 1989. Computer simulation for teaching membrane potential fundamentals.. https://doi.org/10.1016/0020-7101(89)90014-7
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