Microtubule structure at low resolution by x-ray diffraction.

E Mandelkow; J Thomas; C Cohen

doi:10.1073/pnas.74.8.3370

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Microtubule structure at low resolution by x-ray diffraction.

E Mandelkow·J Thomas·C Cohen

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Abstract

Analysis of x-ray diagrams of oriented hydrated cytoplasmic microtubules shows that the tubule wall extends from about 70 to 150 A radially. The central region of the wall appears homogeneous, but the outside surface is subdivided by vertical grooves separating the 13 protofilaments and by a steep 10-fold family of grooves. The inside surface is dominated by the 10-start grooves with no clear subdivision between the protofilaments.

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Animals Brain Cattle Microscopy, Electron Microtubules Models, Structural X-Ray Diffraction Journal Article Research Support, U.S. Gov't, P.H.S.

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E Mandelkow, J Thomas, C Cohen. 1977. Microtubule structure at low resolution by x-ray diffraction.. https://doi.org/10.1073/pnas.74.8.3370

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