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PubMed · 2733200

[Evaluation of hepatic function by hepatobiliary scintigraphy using factor analysis].

O Shimomura·M Takahashi·A Tsuji·Y Takagi·S Tomiguchi·Y Koga·A Kojima·M Matsumoto·M Hara·Y Hirota
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Abstract

Factor analysis of hepatobiliary scintigraphy using 99mTc-N-pyridoxyl-5-methyltryptophan (99mTc-PMT) was performed, and functional factor of liver parenchyma (FA-hepatogram) was obtained. Two parameters (peak time, T 1/2) were calculated from this hepatogram. A good correlation was obtained between these parameters and ICG-R15; furthermore, these parameters were prolonged in patients with normal volunteers, chronic hepatitis, compensated and decompensated liver cirrhosis in this order. Conventional hepatogram by ROI method (ROI-hepatogram) was not suitable for the evaluation of global liver function in condition such as a large intrahepatic mass, intrahepatic gall bladder, dilatation of biliary tree, and severe liver cirrhosis. But, even in such cases, FA-hepatogram was useful for the evaluation of global liver function.

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Biliary TractFactor Analysis, StatisticalHumansLiverLiver DiseasesLiver Function TestsOrganometallic CompoundsOrganotechnetium CompoundsPyridoxalRadionuclide ImagingTryptophanJournal Article

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O Shimomura, M Takahashi, A Tsuji, Y Takagi, S Tomiguchi, Y Koga, A Kojima, M Matsumoto, M Hara, Y Hirota. 1989. [Evaluation of hepatic function by hepatobiliary scintigraphy using factor analysis].. https://pubmed.ncbi.nlm.nih.gov/2733200/

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