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Active control of intracellular pH.

W F Boron
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Abstract

When the interior of a squid giant axon is loaded with acid, the cell responds by extruding that acid in an energy-requiring process. Our results indicate that this acid extrusion is accomplished by exchanging external HCO3- for internal Cl- at the expense of ATP.

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Acid-Base EquilibriumAdenosine TriphosphateAnimalsAxonsBiological Transport, ActiveCyanidesDecapodiformesDinitrophenolsHydrogen-Ion ConcentrationIn Vitro TechniquesIntracellular FluidJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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W F Boron. 1978. Active control of intracellular pH.. https://doi.org/10.1016/0034-5687(78)90084-1

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