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PubMed · 2790293

Transient increase in plasma catecholamines following hypertonic/hyperosmotic fluid administration in conscious rats.

R G Carroll·G T Clark·M E Whitehurst
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Abstract

Plasma norepinephrine and epinephrine levels were monitored to determine possible alterations of the sympathetic nervous system caused by hypertonic fluid administration. Iv infusion (3.5 ml/kg, 1 min) of 7.5% NaCl/6% Hespan transiently increased both plasma norepinephrine and epinephrine levels to 197 +/- 28% and 220 +/- 30% of control, respectively, at 1 min. These increases were no longer significant 5 or 15 min following infusion. A brief hypotension was also observed immediately following hypertonic fluid administration. Thus, prolonged sympathetic activation does not occur following hypertonic fluid infusion in normovolemic conscious rats.

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AnimalsBlood PressureConsciousnessEpinephrineHypertonic SolutionsInfusions, IntravenousNorepinephrineRatsSympathetic Nervous SystemJournal Article

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R G Carroll, G T Clark, M E Whitehurst. 1989. Transient increase in plasma catecholamines following hypertonic/hyperosmotic fluid administration in conscious rats.. https://pubmed.ncbi.nlm.nih.gov/2790293/

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