[Changes of macrophage function after graded physical loading].

D N Maianskiĭ; N P Voronina

PubMed · 2797901

[Changes of macrophage function after graded physical loading].

Abstract

Intensive physical loading (swimming for 3.5 hours with a load amounting to 4% of body weight for rats and for 1 hour without a load for mice) reduced 5-6-fold the clearing function of the mononuclear phagocyte system of untrained animals. The absorption function of Kupffer's cells diminished 2-fold, whereas clearance through macrophages of the lung interstitium was activated. Kupffer's cells of trained animals (daily swimming for 1 hour for 10 days) acquired tolerance to loading. Preliminary administration of zymosan (3-14 days before intensive physical loading) increased the animals' resistance to stress 2-3-fold.

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Animals Macrophages Mice Mice, Inbred CBA Physical Exertion Rats Rats, Inbred Strains Comparative Study English Abstract Journal Article

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D N Maianskiĭ, N P Voronina. [Changes of macrophage function after graded physical loading].. https://pubmed.ncbi.nlm.nih.gov/2797901/

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