Immunologic abnormalities associated with acute ischemic heart disease (a pilot study).

H S Kaufman; V I Kvitash

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PubMed · 2802265

Immunologic abnormalities associated with acute ischemic heart disease (a pilot study).

H S Kaufman·V I Kvitash

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Abstract

When in vivo and in vitro studies of patients with myocardial infarction (MI) were compared with healthy controls there was significantly diminished cutaneous cellular immunity and numbers of T lymphocytes in patients who suffered MI. This study contrasted patients with MI to controls and to patients with other types of cardiovascular disease. There was a significant difference when control patients were compared with those who failed to survive MI for 4 weeks (P less than .001). Patients who died in less than 1 month had 3.6 times less circulating percent T-cells than age-matched controls. A new method is described for categorization of in vitro T-cells in human subjects. If certain patients with low numbers of T-cells following MI die, perhaps this information may serve to alert the physician to intervene and correct the patient's course to recovery.

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Acute Disease Angina Pectoris Coronary Disease Follow-Up Studies Humans Hypersensitivity, Delayed Myocardial Infarction Rosette Formation T-Lymphocytes Journal Article

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H S Kaufman, V I Kvitash. 1989. Immunologic abnormalities associated with acute ischemic heart disease (a pilot study).. https://pubmed.ncbi.nlm.nih.gov/2802265/

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