Chronic ethanol ingestion selectively affects memory modulation in rats.

C Dalmaz; C Fin; C B Oliveira; I Izquierdo

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PubMed · 2804474

Chronic ethanol ingestion selectively affects memory modulation in rats.

C Dalmaz·C Fin·C B Oliveira·I Izquierdo

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Abstract

Post-training treatment alters memory by different mechanisms. Naloxone enhances memory by antagonism of endogenous beta-endorphin-induced state dependency. Epinephrine facilitates consolidation at low doses and generates state dependency at high doses. Exposure to a session of tones causes retroactive interference through a cognitive effect. The present data show that chronic ethanol ingestion, in rats, inhibited the post-training effect of naloxone and of a high dose of epinephrine on the retention of an inhibitory avoidance task but did not inhibit retrograde interference by a session of tones or retrograde facilitation by a low dose of epinephrine. Therefore, ethanol appears to selectively affect post-training influences related to state dependency.

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Animals Avoidance Learning Body Weight Drinking Escape Reaction Ethanol Female Memory Rats Rats, Inbred Strains Retention, Psychology Comparative Study Journal Article Research Support, Non-U.S. Gov't

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C Dalmaz, C Fin, C B Oliveira, I Izquierdo. 1989. Chronic ethanol ingestion selectively affects memory modulation in rats.. https://pubmed.ncbi.nlm.nih.gov/2804474/

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